The epithelia are part of the innate immunity establishing a physical barrier that allows separating the external environment from the internal environment of the human body, thus limiting the entry of microorganisms that could cause different types of diseases; however, epithelial cells, as the majority population in this tissue, do not remain passive, on the contrary, they participate very actively as sentinels recognizing common molecules among microorganisms through innate immunity receptors, and after their activation, they induce the production of soluble mediators that favor the inflammatory response. The aim of the present review is to show in a general way, the characteristics and molecules that participate in the innate immune response generated by epithelial cells, describing as an example the response to viruses and some particularities that occur in some organs of the human body.
Resúmen
Los epitelios forman parte de la inmunidad innata al establecer una barrera física que separa el medio externo del medio interno del cuerpo humano, de ésta forma, limita la entrada de microorganismos con el potencial de ocasionar diferentes tipos de enfermedades, sin embargo, las células epiteliales como población mayoritaria en este tejido no se mantienen de forma pasiva, al contrario, participan de forma muy activa como centinelas, reconociendo moléculas comunes entre microorganismos a través de receptores de la inmunidad innata y, tras su activación, inducen la producción de mediadores moleculares solubles que favorecen la respuesta inflamatoria. El objetivo de la presente revisión es mostrar, de forma general, las características y moléculas de la inmunidad innata generadas por las células epiteliales en diferentes localizaciones en órganos del cuerpo humano, describiendo como ejemplo la respuesta a la infección viral.
Ene | Feb | Mar | Abr | May | Jun | Jul | Ago | Sept | Oct | Nov | Dic |
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- | - | - | - | - | - | - | - | - | - | 1 | 134 |
Ene | Feb | Mar | Abr | May | Jun | Jul | Ago | Sept | Oct | Nov | Dic |
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29 | 11 | 25 | 21 | 9 | 13 | 20 | 23 | 27 | 29 | 25 | 6 |
Ene | Feb | Mar | Abr | May | Jun | Jul | Ago | Sept | Oct | Nov | Dic |
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14 | 19 | 29 | 17 | 11 | - | - | - | - | - | - | - |
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